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Ebola virus (/ ɛ ˈ b oʊ l ə /; EBOV, formerly designated Zaire ebolavirus) is one of five known viruses within the genus Ebolavirus. Four of the five known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD).
Ebola virus (EBOV) is fatal to Africa as the majority of major outbreaks have emerged from central Africa (Figure 3). EBOV is not only a dangerous virus because it is a virulent pathogen, but also because it spreads rapidly as this virus is easily transmitted between individuals.
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Medical use. As of April 2017, ring vaccination with rVSV-EBOV appeared to be somewhat effective, but the extent of efficacy was uncertain, due to the trial design and elimination of the delayed treatment arm part way through the trial.
Using state-of-the-art approaches for immunogen design, the investigators will use EBOV glycoprotein as a basis for the rational design and production of pan-ebolavirus vaccine candidates to promote broadly protective immune responses that target vulnerable structural sites shared among all ebolaviruses.
Ebola Virus Disease (EVD) is a rare and deadly disease in people and nonhuman primates. The viruses that cause EVD are located mainly in sub-Saharan Africa.
I februar 2014 konstateredes et nyt udbrud af ebola i Guinea i Vestafrika. Udbruddet i Guinea blev identificeret som værende et EBOV-udbrud og havde en mortalitet på 65,5%.
On 23 March 2014, the World Health Organization (WHO) reported on a new outbreak of Ebola virus (EBOV) infection which began in December 2013 in the Republic of Guinea, initially in the Prefecture of Guéckédou , and which would shortly thereafter spread to other West African countries, viz.
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