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Mechanism of action. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases (more avidly C-Raf than B-Raf).
Come agisce Nexavar? Il principio attivo di Nexavar, sorafenib, è un inibitore della protein-chinasi. Esso cioè blocca alcuni ...
Anwendungsgebiete und Zulassung. Sorafenib zählt zu den Orphan-Arzneimitteln und ist seit 2006 für einige wenige Indikationen in der EU zugelassen.
Physician reviewed sorafenib patient information - includes sorafenib description, dosage and directions.
Sorafenib (Nexavar) tyrosine kinase inhibitor targeted therapy side effects, how it's given, how it works, precautions and self care tips for treatment of advanced ...
Nexavar is used to treat advanced renal cell carcinoma. Learn about side effects, interactions and indications.
Use of sorafenib (Nexavar ®) in the treatment of hepatocellular carcinoma: PRODIGE AFEF recommendations
Results of the randomized controlled TACTICS trial demonstrate that transcatheter arterial chemoembolization (TACE) in combination with sorafenib significantly ...
This study will evaluate the efficacy and safety of atezolizumab in combination with bevacizumab compared with sorafenib in participants with locally advanced or ...
The purpose of this study is to compare the overall survival of brivanib versus sorafenib in subjects with advanced HCC who have not received prior systemic therapy.